Introduction to Liquid Based Cell Production

Liquid based examination uses a liquid based thin layer cell detection system to detect cervical cells and perform cytological classification diagnosis. It is currently an internationally advanced cervical cancer cytological examination technology, which significantly improves the satisfaction of specimens and the detection rate of cervical abnormal cells compared to traditional cervical scraping Pap smear examination. The detection rate of cervical cancer cells in cervical cancer prevention cytological examination is 100%, and some precancerous lesions and microbial infections such as mold, trichomonas, virus, chlamydia, etc. can also be detected.

So liquid based technology is an advanced technology applied to women's cervical cancer screening.

Liquid based testing significantly improves the detection quality of cervical cell samples. Due to factors such as blood, mucus, and inflammation, conventional Pap smear often blurs the sample and results in detection errors. In clinical experiments, liquid based testing of the number of cervical cell samples can significantly improve the detection rate of cancer cells and correspondingly reduce the number of times it is necessary to repeat the Pap test, thereby reducing unnecessary concerns caused by patients being retested. The reduction of conventional Pap smear errors is bound to elevate the detection of early-stage cancer to a new stage, and enable those with early-stage cancer to receive early and more effective treatment.

Secondly, atypical squamous epithelial cells refer to cellular changes in cervical cytology that indicate squamous intraepithelial lesions, but their quality and quantity are insufficient to make a clear diagnosis. The handling suggestion is follow-up, and if conditions permit, high-risk HPV-DNA testing for cervical cancer should be conducted. If positive, it does not indicate cervical precancerous lesions, but only indicates a high-risk population that requires further diagnosis through biopsy. Follow up with liquid based cytology after 2 years of negative results.

Clinicians and laboratory technicians have made many improvements in cervical cancer screening and routine Pap smears for a long time. However, the results have been minimal, errors are still inevitable, and the test results are still inaccurate. In routine Pap smear testing, doctors need to manually apply cell samples obtained with a collector onto microsheets. This traditional manual method only collects up to 20% of the cells in the smear, while over 80% of the cell samples remain on the sampler and are discarded along with the sampler. In addition, over 40% of smears may become cloudy and unclear due to the influence of blood, mucus, and inflammatory tissue, as well as artificial artifacts caused by untimely fixation. These shortcomings are the reason for the inaccuracy of most conventional Pap test results.